Pint of Science
Pint of bit.bio: A Pint of Science mini-series. Episode 3: STEM cell cancer treatments with Dr Ramy Ibrahim

Pint of bit.bio: A Pint of Science mini-series. Episode 3: STEM cell cancer treatments with Dr Ramy Ibrahim

June 28, 2021

Welcome to the third and final episode of our very exciting three-part mini series of the Pint of Science podcast, in collaboration with bit.bio, the cell coding company. The series wraps up with Dr Ramy Ibrahim, bit.bio’s Chief Medical Officer and a leading immuno-oncologist. 

Ramy explores how the field of immuno-oncology has evolved from fringe research to a 2011 breakthrough, when the US FDA approved the first immune therapy treatments for skin cancers, and on to his work as Chief Medical Officer of the Parker Institute for cancer immunotherapy, researching effective cell therapies for solid tumours.

We explore how bit bio caught his attention about bit.bio is the company's examination of cells themselves and how to reproduce them reliably and on a grand scale, and the incredible possibilities this raises for medical treatments. 

Interested in the concept that cells can be reprogrammed? It was certainly an inspiration for the foundation of bit.bio, and you can read a bitesize review of the science that enables the technology to work here: https://bit.bio/resources/bits-of-bio/

 

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The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

For the latest news on Pint of Science UK, visit www.pintofscience.co.uk. If you're listening from elsewhere in the world, go to www.pintofscience.com for more information on what's happening in your country.

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of bit.bio: A Pint of Science mini-series. Episode 2: The Symphony of cells in context with Dr Paul Morrill

Pint of bit.bio: A Pint of Science mini-series. Episode 2: The Symphony of cells in context with Dr Paul Morrill

May 7, 2021

Welcome to the second episode of our very exciting three-part mini series of the Pint of Science podcast, in collaboration with bit.bio, the cell coding company.

From Californian surfer to scientist to entrepreneur, today we're talking to Dr Paul Morrill, Chief Business Officer of bit.bio, who discusses their core purpose - to develop the underlying technologies capable of producing consistent batches of every cell type in the human body. He explains that part of their mission is to be able to reliably grow human cells which will allow new drugs and compounds to be tested in context, to help scientists more accurately understand how they will perform in both healthy and diseased human bodies.

Interested in learning more on how bit.bio applies synthetic biology to generate consistent and scalable stem cell derived human cells for research and drug discovery? Listen to the talk, Coding Cells for Life: Consistent and scalable human
iPSC-derived cells for in vitro disease modelling and drug discovery.

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The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

This year, Pint of Science is going live online! We will be going digital from the 17th-20th May in the UK with a great selection and variety of online Pint of Science events.

If you're listening from elsewhere in the world, go to www.pintofscience.com for more information on what's happening in your country.

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

 

Pint of bit.bio: A Pint of Science mini-series. Episode 1: Coding cells with Dr Mark Kotter

Pint of bit.bio: A Pint of Science mini-series. Episode 1: Coding cells with Dr Mark Kotter

April 7, 2021

Welcome to the first episode of a very exciting three-part mini series of the Pint of Science podcast, in collaboration with bit.bio, the cell coding company.

The series kicks off with Dr Mark Kotter, founder and CEO of bit.bio. Mark is an academic neurosurgeon and scientist at the University of Cambridge, or more accurately these days, a bio engineer. His research specialises in quite literally reprogramming cells and coding them to perform certain activities, by activating certain combinations of genes to switch them from one identity to another.

Mark and the bit.bio team are working to harness the power of stem cells and turn them into medicines by looking at biology in a different way – treating cells like a piece of software. They have developed a unique control system called opti-ox™, that allows them to jumpstart the potential 'programs' within a cell which tell it how to behave (and what kind of cell to be) very effectively.

Traditionally this has been a slow and small-scale process, but bit.bio's technology allows the production of these cells in quantities large enough that it could revolutionise medical treatments for everything from cancer to spinal and brain injuries.


You can find Mark on Twitter @MarkKotter
Interested in precise reprogramming of cells? See the video of bit.bio’s opti-ox™ technology reprogramming stem cells into functional skeletal muscle: https://bit.bio/#opti-ox-technology.

Episode_1_Pint_of_Science_2021-04-06_at_18084...

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The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

This year, Pint of Science is going live online! We will be going digital from the 17th-20th May in the UK with a great selection and variety of online Pint of Science events.

If you're listening from elsewhere in the world, go to www.pintofscience.com for more information on what's happening in your country.

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of Aston: A Pint of Science mini-series. Episode 4: The gendered brain with Professor Gina Rippon

Pint of Aston: A Pint of Science mini-series. Episode 4: The gendered brain with Professor Gina Rippon

September 10, 2020

Welcome to Episode four of a very special mini series of the Pint of Science podcast, in collaboration with Aston University.

In this four episode series, we're meeting with a few of the leading lights of research at the university – some you may know if you've been to a Pint of Science talk, and some you may not. We'll be talking about their research, what makes them tick, how they are changing the world for the better and pushing the boundaries of the understanding of humankind... You know, the day to day stuff.

If you're listening to this and you're maybe inspired to learn more about these scientists' fields or STEM courses in general, head to www.aston.ac.uk for more information.

In episode 4, we’re meeting Professor of Cognitive Neuroimaging Gina Rippon, from the School of Life & Health Sciences at Aston University.

Among her work, Gina specialises in brain development and the idea of the ‘gendered brain’; that it’s predominantly society, rather than our biology, which determines how and why men and women behave differently.

She’s spent much of her career looking at these differences through a scientific brain, and examining how everything from the toys we play with to the problems we solve in our lives lead our brains to slot us into the roles expected of us.

 

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The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

This year, Pint of Science is going live online! We will be going digital on the evenings of 7-9th September with a great selection and variety of online Pint of Science events. 

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of Aston: A Pint of Science mini-series. Episode 3: Stem cell technology with Dr Eric Hill

Pint of Aston: A Pint of Science mini-series. Episode 3: Stem cell technology with Dr Eric Hill

September 10, 2020

Welcome to Episode three of a very special mini series of the Pint of Science podcast, in collaboration with Aston University.

Over the next four episodes, we're meeting with a few of the leading lights of research at the university – some you may know if you've been to a Pint of Science talk, and some you may not. We'll be talking about their research, what makes them tick, how they are changing the world for the better and pushing the boundaries of the understanding of humankind... You know, the day to day stuff.

If you're listening to this and you're maybe inspired to learn more about these scientists' fields or STEM courses in general, head to www.aston.ac.uk for more information.

In this episode, we’re meeting Dr Eric Hill, senior lecturer and member of Aston University’s Biosciences Research Group.

Eric does something pretty remarkable sounding on a day to day basis –he 3D prints brains. Not the whole thing, but his team uses very sensitive 3D printers and stem cell technology to implant neurons and other brain cells in order to create working models of parts of the brain, which they use to study the cause and effects of early onset Alzheimer’s and other terrible degenerative conditions. It’s an incredible technology which could have wide-reaching effects on diagnosis and scientific research.

We’re also going to be talking about the incredible experience of growing your first beating heart cells in a dish, and the future of stem cell therapies and possible treatments for everything from epilepsy to heart failure in years to come.

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The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

This year, Pint of Science is going live online! We will be going digital on the evenings of 7-9th September with a great selection and variety of online Pint of Science events. 

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of Aston: A Pint of Science mini-series. Episode 2: The Psychology of allergies with Dr Rebecca Knibb

Pint of Aston: A Pint of Science mini-series. Episode 2: The Psychology of allergies with Dr Rebecca Knibb

September 10, 2020

Welcome to Episode two of a very special mini series of the Pint of Science podcast, in collaboration with Aston University.

Over the next four episodes, we're meeting with a few of the leading lights of research at the university – some you may know if you've been to a Pint of Science talk, and some you may not. We'll be talking about their research, what makes them tick, how they are changing the world for the better and pushing the boundaries of the understanding of humankind... You know, the day to day stuff.

If you're listening to this and you're maybe inspired to learn more about these scientists' fields or STEM courses in general, head to www.aston.ac.uk for more information.

In episode 2, we’re meeting Dr Rebecca Knibb, of Aston University’s School of Psychology.

Rebecca researches the psychology of allergies, and looks at ways people who suffer with intolerances and other conditions such as asthma can life happier, more confident lives. It’s something which affects millions of people throughout the UK, and can make the most simple activities, like getting on a bus or buying a coffee, a daily ordeal.

Rebecca’s work focusses on helping these people, and their families, as well as assisting in research into future therapies which could potentially save lives, as well as a huge amount of stress and anxiety.

If you're listening to this and you're maybe inspired to learn more about these scientists' fields or STEM courses in general, head to aston.ac.uk for more information.

Pint of Aston episode 2

 

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The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

This year, Pint of Science is going live online! We will be going digital on the evenings of 7-9th September with a great selection and variety of online Pint of Science events. 

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of Aston: A Pint of Science mini-series. Episode 1: Antibiotic resistant diseases with Dr Jonathan Cox

Pint of Aston: A Pint of Science mini-series. Episode 1: Antibiotic resistant diseases with Dr Jonathan Cox

September 10, 2020

Welcome to Episode one of a very special mini series of the Pint of Science podcast, in collaboration with Aston University.

Over the next four episodes, we're meeting with a few of the leading lights of research at the university – some you may know if you've been to a Pint of Science talk, and some you may not. We'll be talking about their research, what makes them tick, how they are changing the world for the better and pushing the boundaries of the understanding of humankind... You know, the day to day stuff.

If you're listening to this and you're maybe inspired to learn more about these scientists' fields or STEM courses in general, head to www.aston.ac.uk for more information.

In episode 1, we're meeting a man whose leading the fight against bad bugs and some of the most destructive diseases we're fighting today. Dr Jonathan Cox is leader of the Mycobacterial Research Group at Aston University. He specialises in antibiotic resistant diseases such as Tuberculosis, or TB, and has dedicated his career to finding ways to defeat these hardy bugs. He's also a Pint of Science festival grandee to boot, so pull up a drink of your choice, and get ready for a Pint of Science with Dr Jonathan Cox.

Pint of Aston episode 1 thumbnail

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The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

This year, Pint of Science is going live online! We will be going digital on the evenings of 7-9th September with a great selection and variety of online Pint of Science events. 

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of Science Podcast - Prof Jim Smith, Radiation and Environmental Scientist studying Chernobyl [Series 2 - Episode 2]

Pint of Science Podcast - Prof Jim Smith, Radiation and Environmental Scientist studying Chernobyl [Series 2 - Episode 2]

July 7, 2020

Series 2 Episode 3 sees Callam and Jim meet Professor Jim Smith, Environmental Scientist at the School of the Environment, Geography and Geosciences at the University of Portsmouth.

 

Jim started his career as a physicist, and has spent the last 30 years working in the Chernobyl disaster zone in Ukraine and Belarus. His work is somewhat unusual in combining physics and the science of radioactive decay, with environmental science and the effects of said radiation on wildlife populations.

Jim's something of an expert on what happens to nature when humans are taken out of the picture - as they have been in the Chernobyl exclusion zone and, to an extent, in much of the rest of the world by the Covid-19 lockdown.

Oh, and he's also developed Atomik Vodka, the first spirit made from wheat grown in the exclusion zone.

The Pint of Science podcast meets scientists and science writers at a safe social distance around the UK (and the rest of the world) to find out about their lives, their universe, and everything.

Series 2 sees us target more topical stories and discuss the science around them. Like what we do? Let us know using the hashtag #pintcast. And be sure to subscribe to us and rate us on your favourite podcasting platform!

SubscribeSpotifyTuneInStitcherApple

The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

This year, Pint of Science is going live online! We will be going digital on the evenings of 7-9th September with a great selection and variety of online Pint of Science events. 

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of Science Podcast - Dr Paula Koelemeijer, Global Seismologist [Series 2 - Episode 2]

Pint of Science Podcast - Dr Paula Koelemeijer, Global Seismologist [Series 2 - Episode 2]

May 20, 2020

Series 2 Episode 2 sees Callam and Jim meet Dr Paula Koelemeijer, Global Seismologist and Royal Society University Research Fellow and Lecturer at Royal Holloway University of London. Paula studies the seismic activity of the Earth thousands of kilometres below the surface, but recent events much closer to home have had a surprising positive effect on her work.

Due to the Covid-19 pandemic and much of the world being in lockdown, Seismologists have been getting far clearer signals from within the Earth, because of less disruption from on top of it. Known as Anthropogenic Noise, the racket that humans make by working, travelling and moving around makes the work of those studying the Earth very difficult. With less noise comes significantly clearer signals - from which we can filter out the noise when it eventually returns.

Oh, and we also talk about the earthquakes caused by Lionel Messi scoring, quakes on the Moon and Mars, using tremors to stop elephant poaching, and tracking the shakes caused by Rolling Stones concerts. It really is a wide conversation, this one!

The Pint of Science podcast meets scientists and science writers at a safe social distance around the UK (and the rest of the world) to find out about their lives, their universe, and everything.

Series 2 sees us target more topical stories and discuss the science around them. Like what we do? Let us know using the hashtag #pintcast. And be sure to subscribe to us and rate us on your favourite podcasting platform!

SubscribeSpotifyTuneInStitcherApple

The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

Pint of Science Podcast - Professor Nick Chater - Professor of Behavioural Science [Series 2 - Episode 1]

Pint of Science Podcast - Professor Nick Chater - Professor of Behavioural Science [Series 2 - Episode 1]

May 5, 2020

Welcome to series two of the Pint of Science Podcast! We're very excited to have Nick Chater, Professor of Behavioural Science at Warwick Business School as our first guest, from a safe social distance. Nick is the author of The Mind is Flat: The Illusion of Mental Depth and The Improvised Mind, and an advisor to the UK Government’s Behavioural Insights team (‘The Nudge Unit’). He's also scientist in Residence for BBC Radio 4’s The Human Zoo.

This week, Callam and Jim talk to Nick about the psychology of lockdowns around the world - not why we need to distance, but how we convince people it's a good idea and something they should take part in - as well as how to message effectively, and how to not...

The Pint of Science podcast meets scientists and science writers at a safe social distance around the UK (and the rest of the world) to find out about their lives, their universe, and everything.

Series 2 sees us target more topical stories and discuss the science around them. Like what we do? Let us know using the hashtag #pintcast. And be sure to subscribe to us and rate us on your favourite podcasting platform!

SubscribeSpotifyTuneInStitcherApple

The Pint of Science podcast is a part of the Pint of Science Festival, the world's largest science communication festival. Thousands of guests and speakers descend on pubs in hundreds of cities worldwide to introduce science in a fun, engaging, and usually pint-fuelled way.

You can donate and help Pint of Science through these incredibly challenging times. For obvious public health reasons, we are recording remotely at the moment - but we hope to be back in the pub very soon (and very safely).

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